How do you do risk stratification for patients with light-chain-only MGUS?  

This is a great question, Dr. @Chen. Apologies for the delay in responding.Light-chain disease is not as clearly defined as heavy-chain disease.There is some guidance here based on current studies, such as Maeng et al., PMID 40295472, revised free light chain reference intervals enhance risk stratif...

I agree 100% with @Monique Hartley-Brown - we don't have decades of experience with LC-only MGUS the way we do with traditional MGUS, so our prognostic tools aren't quite as refined. Serial monitoring can be quite helpful here.I see the poll above that commented on age-adjusted and renal-adjusted ra...