How do you do risk stratification for patients with light-chain-only MGUS?

This is a great question, Dr. @Dr. First Last. Apologies for the delay in responding.

Light-chain disease is not as clearly defined as heavy-chain disease.

There is some guidance here based on current studies, such as Maeng et al., PMID 40295472, revised free light chain reference intervals enhance ri...

I agree 100% with @Dr. First Last - we don't have decades of experience with LC-only MGUS the way we do with traditional MGUS, so our prognostic tools aren't quite as refined. Serial monitoring can be quite helpful here.

I see the poll above that commented on age-adjusted and renal-adjusted ratios fr...