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How do you manage a soft tissue sarcoma arising from neurofibromas (NF1)?

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Mednet Member
Mednet Member
Radiation Oncology · Florida Cancer Affiliates / The US Oncology Network

Great question! Sarcoma (STS) arising in the setting of NF1 can be challenging.

I usually recommend for preop XRT, image-guided RT for STS should be 50 Gy in 2 Gy/fx:

GTV = MRI T1 plus contrast images

CTV for Intermediate-to-High Grade Tumors ≥ 8 cm: CTV = GTV and suspicious edema (defined by MRI T2 im...

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