How do you manage ovarian suppression for premenopausal patients with HR+/HER2 positive breast cancer?
Does lymph node positivity change your management?
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In premenopausal patients with node positive, HR+/HER2 positive breast cancer who undergo oopherectomy, which anti-estrogen therapy would you choose thereafter?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · Icahn School of Medicine at Mount Sinai
Answered on
Oophorectomy and GnRH agonist are two options for ovarian suppressive therapy. There are two fundamental differences between these options. First, GnRH monthly, and especially the 3-month depot preparations, will incompletely suppress estradiol levels in some women. 17% to 25% of women on monthly Gn...
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