How do you manage patients who develop de novo or recurrent skin cancers (SCC or BCC) while on lenalidomide?
Do these events mandate discontinuation of lenalidomide therapy or switching to a different agent? Can appropriate therapy for these skin cancers be rendered as needed while continuing the drug?
Does your choice above differ based on the indication for lenalidomide therapy (eg maintenance post-transplant vs front line therapy)?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · Winship Cancer Institute of Emory University
Answered on
The most common hematologic malignancies in patients who have undergone stem cell transplantation and then lenalidomide maintenance are acute myeloid leukemia, myelodysplastic syndrome, and rarely acute lymphocytic leukemia (Palumbo A, Lancet Oncol, 2014, PMID 24525202 & Aldoss I, Leukemia, 2019).
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