How do you manage prophylactic antimicrobial medications in patients who undergo ATG/cyclosporine/eltrombopag induction for severe aplastic anemia?
What would you recommend within the first year after ATG and thereafter if still maintained on cyclosporine?
1 Answer
Mednet MemberInvited Expert
Hematology · UMass Chan Medical School
Answered on
Yes for prophylactic antibacterials after ATG/cyclosporine and eltrombopag treatment of AA.
Antiviral with valtrex 500mg oral twice daily and PJP prophylaxis while on immunosuppression with cyclosporine.
Antibacterial with levofloxacin and antifungal prophylaxis with posaconazole 300mg oral daily or equivalent only if ANC <500 until recovery to >500.
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