How do you manage the severe adverse drug reaction of central serous retinopathy with MEK inhibitors?

Fortunately, the ICSC-like association of subretinal fluid with MEK inhibitor exposure is usually reversible after cessation of the drug. When working with this class of medications, it is important to coordinate care with the treating oncologist.

If a patient presents with subretinal fluid and is o...

Whether to stop the medication should be based on the patient’s vision and symptoms.