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How do you manage the side effects of ropeginterferon alfa 2b for polycythemia vera patients?

Do you have preferred therapies for managing muscle weakness, myalgias, or fatigue? Have you added metformin to manage these symptoms?
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What is your first line in managing side effects of ropeginterferon alfa 2b?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Massachusetts General Hospital
Answered on

Great question. Although ropeginterferon is better tolerated than other interferons, it is still associated with adverse events. If counts are controlled, I would recommend lowering the dose or spacing out the dosing interval, as that usually helps. For flu-like symptoms, I recommend pre-emptive man...

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