How do you monitor blood glucose levels in patients without preexisting diabetes who are starting capivasertib?
Do you check glucose levels during the 4 days while the patient is taking the drug, or once weekly, or other?
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How do you monitor glucose in patients without preexisting diabetes who are starting capivasertib?
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Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
Answered on
Capivasertib inhibits phosphorylation of downstream AKT substrates. By blocking AKT, an obligatory node in insulin signaling that mediates GLUT4-dependent glucose uptake in muscle and adipose tissue and suppresses hepatic glucose production, capivasertib reduces peripheral glucose uptake and increas...
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