How do you select between antipsychotics in the treatment of delirium refractory to nonpharmacological management in hospitalized older adults with dementia?
From a geriatrics harm-reduction standpoint, can we recommend any particulars regarding dosing or selection of therapies when used as a last resort?
Answer from: at Academic Institution
I have learned that antipsychotic selection is very institution-based/variable.Traditionally, at the Brigham, we have preferred Seroquel because it is titratable and avoids issues if the patient has underlying Parkinson's. However, now that Zyprexa is available in IV form, house staff often prefer t...
For many years, I have had great success with Seroquel IR tablets because they are titratable. Because of the many potential side effects, I start low dose, usually 6.25 mg-12.5 mg in the morning and 12.5 mg-25 mg in the evenings, and titrate to effect, watching for drowsiness and orthostasis as wel...