How do you select the concurrent cisplatin dose and schedule when treating locally advanced endometrial cancer with chemoradiation?
2 Answers
Mednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network
For locally advanced endometrial cancer treated with pre operative or definitive intent, we use weekly cisplatinum at 40mg/m2.
Mednet Member
Gynecologic Oncology · Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Just like @Dr. First Last, for most patients, I give cisplatin 40mg/m2 weekly as a radiosensitizer for definitive chemo radiation in uterine cancer. If the patient has poor renal function or is frail, then I will typically give carboplatin AUC 2 weekly.