How do you select which patients with H&N primary tumors benefit from proton therapy?

Surprising to see that the expert opinion after TORPEdO results is that IMPT is also a great choice. Granted, it contradicts the MDACC-led study, but we should have nuance and critical analyses.

The rates of feeding tube dependence in the IMRT arm in the MDACC-led study are astronomical. I have neve...

Selection for treatment with proton therapy for patients with head and neck tumors should be considered when a dosimetric advantage exists that can improve the clinical outcomes in head and neck cancer patients. The dosimetric differences between the two radiation modalities in the oral cavity, brai...

NCCN has great guidelines.

Well, what insurance does the patient have?

Joking aside, this is very important as the prices are quite high and vary from 5-10x by center, as noted in a timely article by Prasad et al., PRO 2022.

"List prices for PT differ dramatically between institutions and regions without obvious explanation, ...

Paranasal sinus, nasopharynx, oropharynx, skin with symptomatic V1 and V2 invasion, plus the occasional oral cavity.