How do you sequence short course radiation for locally advanced rectal cancer when using the total neoadjuvant approach?  

When using short course RT, the NCCN guidelines currently recommend short course RT followed by chemotherapy, followed by surgery. Many surgeons are hesitant to allow a 4 month interval between radiation and surgery (given a worry for disruption and scarring of tissue planes). Is this a valid concern? Or, is a 4 month interval too short an interval to see significant disruption of surgical planes?



Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Community Practice
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Radiation Oncologist at Washington University School of Medicine
One should note that the preoperative chemotherapy...
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Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Community Practice
Comments
Radiation Oncologist at Washington University School of Medicine
Actually Michel et al found that, in their study, ...
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