How do you taper corticotropin injections (Acthar) in patients with rheumatologic disease?
Answer from: at Community Practice
All rheumatologists will at some point in their career have a patient or two or three who do not tolerate any of the usually available steroids (po prednisone, po methylprednisolone, triamcinolone IM, IM methylprednisolone/dexamethasone, IV methylprednisolone) and who have ongoing active inflammator...
In part, it would depend on whether the patient is already on steroids. ACTHAR has 2 components to its MOA - an ACTH component and an action secondary to MSH.
Purely from a non-Endocrinologist:
When ACTHAR is used without an underlying steroid on board, the HPA Axis (adrenal gland and probably the...