How do you treat a fit patient with a solitary pulmonary nodule (2cm) which is biopsy-proven small cell lung carcinoma?

Topics: Thoracic Malignancies • Medical Oncology • NCI-CCC Tumor Board Question • Indiana University

PET-CT and Brain MRI are negative for other evidence of disease.

Answer from: Medical Oncologist at Academic Institution

Clinical stage I SCLC is vey rare but does happen. In the past this was referred to as "VERY" limited disease. We would recommend surgery, either lobectomy or just a wide wedge resection but with nodal evaluation. This patient would need adjuvant chemo with 4 courses of cisplatin (or carboplatin) + ...

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Medical Oncologist at Wexner Medical Center at The Ohio State University
If the patient is found to have N2 positive diseas...

Answer from: Medical Oncologist at Community Practice

I agree with @Lawrence H. Einhorn. In my experience, these "very" limited SCCLCa are discovered incidentally when an isolated, growing pulmonary nodule has been resected. Agree completely with respect to adjuvant chemoTx.

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