How do you treat locally advanced medullary thyroid cancer with postoperative RT?
What dose and fractionation is appropriate for medullary thyroid carcinoma with extrathyroid extension, bilateral cervical lymph node levels 2-5 with extranodal extension, paratracheal node involvement with extranodal extension, and thymus involvement s/p excision with positive margins throughout? Gross unresected disease remains in the mediastinum levels 4, 7, and bilateral hilar lymph nodes. Also what is the appropriate literature for treatment guidance?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · University of Michigan
Answered on
Medullary thyroid cancer typically presents with extensive LN metastases, and this case represents a typical very advanced case. Cases of more localized cancers which I have treated were characterized by adequate control of the irradiated disease, however, in all such patients disease progressed in ...
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