How do you treat pleomorphic rhabdomyosarcoma in an adult?

Rhabdomyosarcoma is a rare malignancy, with ~350 cases annually in the United States, but most commonly occurs in children. Thus, adult rhabdomyosarcoma is exceedingly rare. As a result, there are very limited data on adult rhabomyosarcoma to guide treatment decisions and much is extrapolated from the pediatric literature. What we do know is that clinical outcomes of adult rhabdomyosarcoma have been reported to be worse than outcomes for pediatric rhabdomyosarcoma. And furthermore, in adults, re...