How do you utilize liver assistive devices in the management algorithm of patients with acute liver failure?

In the setting of severe ALF, we use 2 extracorporeal liver support strategies, which include high dose CRRT for the management of hyperammonemia, and plasma exchange as an add on to CRRT if the patient develops shock.

The goal of high-dose CRRT (with high dose at our center defined as at least 60 m...