How do you utilize methotrexate and/or hydroxychloroquine in the setting of limited scleroderma/CREST?

Thank you for this great question!

The use of immune-suppression in systemic sclerosis is generally reserved for progressing skin sclerosis, progressive ILD, inflammatory arthritis, inflammatory myositis, and myocarditis. These manifestations have a significantly higher prevalence in diffuse cutaneou...