How does the FDA safety warning on the cardiac effects of lamotrigine, based on in vitro data, inform your clinical practice?

Topics: Epilepsy • Neurology

This question is intended to include consideration of cardiac diagnostic screening, as well as initiation & maintenance of lamotrigine, in epilepsy patients with comorbid cardiac disease.

Answer from: at Community Practice

I am aware of it and will be careful in using it with patients who have any conduction abnormalities, though that doesn't mean I won't use it. I have been using it for many years (my program during fellowship was a research site for bringing it to the US) and never had a problem with it.

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at UF Health
I have never had an issue with it, however, many o...

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