How have you used HHIs as neoadjuvant/adjuvant therapies?   

I am presuming that the question is directed towards Basal cell cancer. We don't use HHI in an adjuvant setting, but sometimes in the neoadjuvant setting, when the risk of getting a positive margin is high. I prefer alternate-day dosing of vismodegib (less muscle cramps, hair preservation, less nau...