How often do you believe para-aortic radiotherapy in addition to pelvic radiotherapy causes additional treatment breaks due to acute toxicity?

I would agree with @Dr. First Last that with IMRT and accurate definition of targets and organs at risk, that treatment can be delivered successfully. In patients who have had prior chemotherapy, attention to weekly blood counts is imperative. It is usually the platelet counts that pose a challenge....

It certainly adds to acute GI and myelotoxicity. All previous studies which showed acute morbidities and treatment interruptions are with conventional 3D technique. There is no good comparative study in modern era. With IMRT small bowel and marrow doses are reduced significantly which does translate...