How should the results of the ADVOCATE trial be applied in AAV patients who receive rituximab induction and maintenance therapy?

The following answer was jointly drafted by Dr. Peter Merkel and Dr. David Jayne:

The data from ADVOCATE indicate that patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) treated with avacopan 30 mg twice daily and prednisone placebo were able to achieve remission w...