How would the updated results of ECOG 3311 influence your adjuvant RT recommendations for HPV+ OPSCC?

Would you consider de-escalation to 50 Gy for patients who meet the intermediate-risk criteria? Are you more likely to offer adjuvant RT to patients with 1 positive node as the sole indication?

Answer from: Radiation Oncologist at Academic Institution

This question refers to this manuscript (Burtness et al., PMID 40493877), which is a 4.5-year follow-up of ECOG E3311.The results broadly mirror those seen in previous reports. The most notable novel finding reported is that among patients with low-risk features (who did not get any adjuvant RT), th...

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Radiation Oncologist at University of Kansas School of Medicine
Agree completely on all points. I share some of th...

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How would the updated results of ECOG 3311 influence your adjuvant RT recommendations for HPV+ OPSCC?

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