How would you advise medical oncologists who recommend checkpoint inhibitors for a patient with baseline Type 1 diabetes?
Some oncologists may have concerns that checkpoint inhibitors may diminish islet cell reserve and lead to worsening DM control.
Answer from: at Community Practice
T1DM means near-complete beta-cell deficiency. These patients aren’t making enough insulin to impact blood glucose control. We always treat the cancer first, with the most appropriate medications, and worry about the diabetes later. We even advise oncologists to continue ICIs after a patient d...