How would you approach a cutaneous squamous cell carcinoma with primary tumor completely excised, but multiple foci of LVI at the peripheral specimen margin and no other high-risk features?

In a prospective study that assessed clinical and pathological risk factors for primary tumor site recurrence after margin negative excision of cutaneous squamous cell carcinoma, the presence of desmoplasia was reported to be the primary variable associated with this event. The authors specified tha...

We handle H&N skin cancers differently from limbs and trunk. For H&N, if there is extensive LVSI that’s already an indication to consider PORT with a generous margin in my mind, especially in an immunocompromised patient. A re-resection is not going to change that. Limbs and trunk are more forgiving...