How would you approach a mucinous adenocarcinoma of the anal verge without anal canal involvement, status post excision with positive margins but without the possibility of additional surgery?

Topics: Radiation Oncology • Gastrointestinal Cancers

Given this rare histology, would you treat this patient as a skin cancer or as an anal adenocarcinoma with inguinal nodal coverage?

Answer from: Radiation Oncologist at Academic Institution

The nodal drainage is dependent primarily on the anatomy and not the histology (the histology can determine the likelihood of nodal spread). If the tumor is truly not involving the anal canal one has to assume that this is a cancer originating in the skin and I would manage it as a skin cancer...

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Radiation Oncologist at Mercy Clinic Radiation Oncology
A positive margin means that some treatment should...

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