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Topics:
Rheumatology
•
Vasculitis
How would you approach a patient with EGPA, with main manifestations of asthma, nasal polyposis, and mononeuritis multiplex, who has clinically responded to rituximab, yet has persistently high eosinophilia (>40%)?
Would you add mepolizumab for the eosinophilia?
Related Questions
How do you treat IgA vasculitis with gastrointestinal involvement?
How do you approach tapering of tocilizumab used for a history of GCA with vision loss?
How would you approach a patient with high CRP, rising liver enzymes and new biopsy proven liver granulomas 6 months after starting methotrexate and Rituximab therapy for ANCA vasculitis?
Should patients starting cyclophosphamide be screened routinely for latent tuberculosis (TB)?
What is your approach to treating IgA nephropathy in patients who also have IgA vasculitis?
Do you continue PJP prophylaxis indefinitely in patients on rituximab maintenance therapy?
How would you manage a patient with Takayasu arteritis controlled on TNFi who develops erythema nodosum that is only partially responsive to NSAIDs?
How would you interpret the presence of both high titer anti-PR3 and anti-MPO antibodies in a pANCA positive patient with evidence of small vessel vasculitis?
Do you always pursue biopsy confirmation before diagnosing IgA vasculitis?
How would you approach a male in his 60s with bilateral optic perineuritis/neuritis on MRI, steroid-responsive bilateral jaw pain, normal ESR/CRP, negative temporal artery biopsy, and elevated IgG4?