How would you approach a patient with ER+,HER2- T4N0 breast cancer with chest wall involvement?
Role of neoadjuvant TC vs. anthracycline based regimen?
Answer from: Medical Oncologist at Academic Institution
In a patient with locally advanced ER positive HER2 negative breast cancer, requiring neoadjuvant therapy, I would use third generation chemotherapy such as AC followed by paclitaxel (often in a dose dense fashion), as long as there are no contraindication to anthracycline based regimen. This EBCTCG...
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