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How would you approach a patient with high CRP, rising liver enzymes and new biopsy proven liver granulomas 6 months after starting methotrexate and Rituximab therapy for ANCA vasculitis?

Could the new liver granulomas due to MTX Hepato toxicity?
1 Answer
Mednet Member
Mednet Member
Rheumatology · University of Chicago
Answered on

What does the liver biopsy show in detail? I'd be far more worried about infection than AAV. Sarcoid could also present this way. How did they get the AAV diagnosis?

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