How would you approach a patient with prostate cancer with PSMA+ non-regional lymph nodes?

2 Answers

Mednet Member

Radiation Oncology · Case Western Reserve University/ University Hospitals Seidman Cancer Center

If we take the question at face value, this is a patient with de novo mHSPC and the treatment recommendation would be ADT (level 1) + ARPI (level 1) + RT to primary (level 1) and consideration of RT to metastatic sites (level 3 data).

However, I would use one of the multiple PSMA-RADS-like scoring sy...

Mednet Member

Radiation Oncology · Varian Medical Systems/Allegheny health network

If non regional nodes are common iliac or lower pa nodes then favor definitive management with RT to nodal region along with the prostate.