How would you approach a post-menopausal female with both a previously HR+ HER2- breast cancer and HR- HER2+ breast cancer with new brain metastasis?

The treatment of brain metastasis from breast cancer depends on a number of factors: number of metastases, biology of the cancer, status of extracranial disease, and performance status. From the question, it sounds like her performance status is good and she does not have progressive extracranial di...