How would you approach a pre-viable pregnant patient in the second trimester with metastatic ovarian cancer who wants to keep the pregnancy?  

I would recommend neoadjuvant chemotherapy and co-manage with maternal-fetal medicine to try to optimize the outcome for both mom and baby. Typically, we will start chemotherapy (platinum-based) after organogenesis is complete and continue q21 days until about 3-4 weeks before planned delivery. Once...