How would you approach a referral for concern for hemochromatosis with ferritin elevation but otherwise normal iron studies?

Interesting questions, but lack of specifics about the degree of elevation and what constitutes normal iron studies makes it difficult to directly answer this question. However, there are well-recognized causes of elevated ferritin due to non-iron overloaded conditions, including increased apoferritin synthesis/secretion due to malignancy, cancers, lymphoma, Gaucher disease, and hereditary hyperferritinemia-cataract syndrome. Elevation can also be seen in patients with liver injury due to any ca...