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How would you approach multiply recurrent prostate cancer in a patient who has had both LDR and salvage HDR?

What would you consider if the recurrence occurs multiple times in the prostate? Salvage surgery if a candidate? HIFU or cryo? ADT?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of New Mexico School of Medicine
Answered on

Very carefully! The risk of GU and GI toxicity from any salvage therapy after both LDR and salvage HDR is very high. If there is a focal lesion identified on MR/PSMA that is distant from the bladder, urethra, and rectum, then maybe you can try a focal treatment. I'd be very careful because the risk ...

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