How would you approach post op management of a patient s/p BSO for cystic pelvic mass with fallopian STIC lesion on final pathology?

STIC lesions are considered precursors to ovarian cancer. The role of surveillance and chemotherapy is unclear. In a comprehensive review of 78 women with isolated STIC lesions, Patrono et al found 3 patients with subsequent primary peritoneal cancer among the BRCA patients with a STIC lesion; this ...

This is a great question! There are no definitive management criteria for patients with isolated serous tubal intraepithelial carcinoma (STIC) lesions. The incidence at the time of risk-reducing salpingo-oophorectomy (RRSO) ranges from 0.6 to 7% in women with BRCA1/BRCA2 mutations. In patients under...