How would you approach systemic treatment of oligometastatic recurrence following surgical removal of the single area of metastasis in a patient with ER+ (20-30%), PR-negative, HER2-negative breast cancer?

The oligometastatic recurrence occurred 10 years after the initial breast cancer diagnosis and involved a single pulmonary nodule.

Answer from: Medical Oncologist at Academic Institution

I would most likely start the patient on endocrine therapy and a CDK4/6 inhibitor. Even though the response rate is lower with this approach in patients with lower hormone receptor-positive breast cancer, it can still be a reasonable option, and it would avoid chemotherapy-related risks and toxiciti...

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Medical Oncologist at CompHealth
I would also send the patient to the rad onc for a...

Medical Oncologist at Los Angeles VA Medical Center
Granted, this Q&A linked here deals with TNBC;...

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How would you approach systemic treatment of oligometastatic recurrence following surgical removal of the single area of metastasis in a patient with ER+ (20-30%), PR-negative, HER2-negative breast cancer?

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