How would you approach therapy for a young, fit patient with alveolar rhabdomyosarcoma involving the anterior nasal vault/sinuses in the absence of available clinical trials?

Topics: Radiation Oncology • Pediatric Oncology • Sarcoma • Medical Oncology • AYA

Presented with mass projecting into right/left anterior ethmoid complex

Answer from: Medical Oncologist at Academic Institution

The patient should be risk stratified (as per the Intergroup Rhabdomyosarcoma Study Group classifications) and treated with multimodality therapy, including chemotherapy and likely definitive radiotherapy, depending on the specific location. Surgery is also a consideration, but these are generally c...

Comments

Radiation Oncologist at Stanford University
I agree with this answer, just adding a few though...

at Geisinger Clinic
Given the alveolar fox 01 fusion positive histolog...

Medical Oncologist at Perlmutter Cancer Center of NYU Langone Health
Can you please comment on the recommendation to gi...

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