How would you approach treatment for fulminant RA-associated ILD?
Would you discontinue Methotrexate and TNF inhibitors even if previously no side effects from these medications, and would you consider Cyclophosphamide as a treatment option?
Any evidence based-approach or expert opinion for fulminant ILD non responsive to high dose corticosteroids?
1 Answer
Mednet MemberInvited Expert
Rheumatology · Harvard Medical School
Answered on
Even though this hypothetical patient has tolerated methotrexate (MTX), I would probably stop it since MTX can directly scar lung parenchyma and continuation of it may confuse the clinical picture. The data for adverse lung toxicity with TNFi drugs is less clear, so I would consider maintaining it. ...
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