How would you approach treatment of DLBCL in a patient on hemodialysis?

For R- CHOP based therapy it can be administered the day before dialysis with no dose adjustments. Only Cyclophosphamide has renal clearance and should be reduced by 50%.

For more aggressive regimens it becomes more challenging as there is not enough data. This is what we would consider doing for E...

For elderly patient on HD R-mini CHOP day before HD is feasible.