How would you approach treatment of DLBCL in a patient on hemodialysis?
2 Answers
Mednet Member
Medical Oncology · Columbia University Medical Center
For R- CHOP based therapy it can be administered the day before dialysis with no dose adjustments. Only Cyclophosphamide has renal clearance and should be reduced by 50%.
For more aggressive regimens it becomes more challenging as there is not enough data. This is what we would consider doing for E...