How would you approach unresectable synovial sarcoma of the heart ?

The specific situation described is rare and I'm not aware of any data addressing it directly, but there are general principles for cardiac sarcomas that can be helpful.

For cardiac sarcomas, subsite matters for prognosis and treatment. Left-sided more prone to non-lung visceral mets. (In resectable ...

I would add the importance of the brain MRI for staging AND surveillance, particularly for left sided tumors. The incidence of brain metastases for cardiac sarcomas is quite high and often occurs within 1 year of diagnosis. This is probably a physiologic consequence and not a unique tropism of cardi...