How would you counsel a patient who will undergo breast irradiation in which a large port wine stain is overlying the breast?

Port-wine stain (PWS) is the second most common congenital vascular malformation characterized as ectatic capillaries and venules in the dermis that clinically appears as a deep red to purple patch on the skin. Like other benign vascular abnormalities (symptomatic hemangiomas of spine, etc) and prior to lasers, RT was used in the distant past to treat these congenital abnormalities. However, there is some data in the literature suggesting that patients with port wine stains treated with ioninzin...

.... it’s difficult to make any assessment with one clinical case study.

Of note: “the anterior chest wall on women is frequently exposed to excessive sunlight at the beach... in many women have early signs of actinic keratosis in severe severe damage present in their early 40s.

I would consult with dermatology to get a baseline assessment of her overall solar damage to the anterior chest wall ....to get a better assessment of her risk from basal cell Carcinoma