How would you decide on VRd vs DRd for initial management of transplant ineligible multiple myeloma?

Both VRd and DRd are reasonable induction regimens for newly diagnosed transplant ineligible patients. DRd has the most direct evidence, as there is a phase III study (MAIA, Facon et al., NEJM, 2019) comparing DRd to Rd with both arms including treatment until progression in a transplant ineligible ...