Topics:
Radiation Oncology • Gastrointestinal Cancers
How would you manage a patient who received neoadjuvant CRT per the CROSS trial for esophageal cancer, but refuses surgery after imaging shows a good radiographic response?
Is there a role for additional treatment?
Answer from: Radiation Oncologist at Community Practice
That's a great question.
It is not evidence based, but with carbo/taxol (CROSS approach), I sometimes will go to 50.4 in case this very situation occurs. It's very well tolerated with conformal approach (the study treated with 41.4 Gy with AP-PA fields).
If it has already happened, and...
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Answer from: Radiation Oncologist at Community Practice
Something to consider when using the xrt dose from CROSS. I generally stick to 45-50.4 for that reason.
Not much one can do if more than a few weeks have passed