How would you manage a patient with essential thrombocythemia and persistent pruritus despite adequate control of CBC with hydroxyurea and aspirin?

Topics: Medical Oncology • Myeloproliferative Neoplasms • Hematology • Benign Hematology • Dermatology • Pruritus

ET is JAK2+

Answer from: Medical Oncologist at Academic Institution

First, I'd make sure to exonerate any other causes of itching. Second, would make sure that supportive treatments like good skin care, anti-histamines, anti-depressants have been tried. I'd then consider if this patient truly has ET, as itching is more common in PV. Ruxolitinib is approved for patie...

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Medical Oncologist at Taussig Cancer Institute
Reminds me of a case from a few years ago. Could n...

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