How would you manage a patient with isolated metastatic high grade sarcoma to inguinal and external nodes in a patient with BRCA+ mutation?
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1 Answers
Mednet Member
Medical Oncology · Emory University
Ovarian cancer treatments can work for BRCA2+ leiomyosarcoma.
This has been published (Seligson et al., PMID 30541756) and I have had a couple of patients with BRCA2+ LMS. I had no luck with PARP inhibitors but one tremendous success with cisplatin, which produced a dramatic response in one heavily p...