How would you manage a Stage IB endometrioid endometrial cancer, status post staging surgery, with a rapid vaginal recurrence <1 month post operatively?

A rapid recurrence like this is unusual, but we have definitely seen it. Cuff recurrences require multidisciplinary management. The most worrisome feature of this patient is the rapidity of recurrence.

For the initial management, I would probably have recommended some kind of adjuvant treatment afte...

Staging workup including PET/CT. If it is the only site of recurrence, I would treat with concurrent weekly cisplatinum with EBRT to include entire common iliac nodes followed by brachytherapy.