How would you manage EBER positive (non-keratinizing) SCCa of unknown primary in the head and neck?

Would you treat it like an “endemic” NPX cancer with induction systemic therapy followed by CRT vs. CRT followed by adjuvant chemo vs CRT alone? What RT treatment volumes will you target?

1 Answer

Mednet MemberInvited Expert

Radiation Oncology · HCA South Atlantic

Answered on

CRT alone as long as neck disease is not multi-level, large, or in the lower neck. I would include bilateral nasopharynx, bilateral RP nodes, and node levels II-V bilaterally.

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