How would you manage LPL with associated AL amyloidosis?

Bendamustine or Cy-Bor-D? Or another induction regimen? Would you consider autologous transplant in CR1 like you would for AL amyloid on its own or with myeloma?

Answer from: Medical Oncologist at Academic Institution

My approach here would depend upon the nature, impact, and severity of the amyloid. Is the LPL IgG or IgM secreting? Is the amyloid causing immediate physiologic harm (renal, cardiac) or asymptomatic radiographic deposits? How much lymphoma and amyloid, respectively? Treatment options include Benda,...

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Medical Oncologist at Loyola University Medical Center
Well stated Dr. @Matasar. This is a very importan...

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How would you manage LPL with associated AL amyloidosis?

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